Febuxostat 144060-53-7 Pharmaceutical Raw Powder for Anti-Gout Drug 40-120 Mg/Day
|FOB Price:||US $0.5-1 / Vials|
|Min. Order:||10 Vials|
|Min. Order||FOB Price|
|10 Vials||US $0.5-1/ Vials|
|Payment Terms:||T/T, Western Union, Money Gram, Bitcion|
- Model NO.: 98%
- Customized: Customized
- Suitable for: Adult
- Purity: >98%
- Delivery Ways: EMS, Hkems, TNT, DHL, FedEx, UPS etc.
- Other Service: We Confirm 98% Clearance, 100% Resending.
- Price: Negotiable( The Greater The Amount, The Greate)
- Transport Package: as You Requst
- Origin: China
- Powder: Yes
- Certification: ISO 9001, USP, BP, RoHS
- State: Solid
- Delivery Port: Express Courier
- Shipment Time: Within 8 Hours After Confirmation of Your Payment
- MOQ: 10 Vials
- Trademark: ShuCan
- Specification: 98% min
Product Name: Febuxostat
Synonyms: FEBUXOSTAT;Tei-6720;2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid;2-[3-Cyano-4-isobutoxyphenyl]-4-methylthiazole-5-carboxylic acid;2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic Acid;2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid;TMX 67;Febuxosta
Product Categories: Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;zjh;API;Febuxostat;TRILIPIX;Other APIs;eterocycles
Mol File: 144060-53-7.mol
storage temp. Refrigerator
CAS DataBase Reference 144060-53-7(CAS DataBase Reference)
Febuxostat is a new generation of xanthine oxidase inhibitor, for the treatment of high uric acid disease (gout) on clinical , the structure is completely different from xanthine oxidase inhibitor drug developed 40 years ago, it is a new and efficient non-purine selective inhibitor of xanthine oxidase. Xanthine oxidase is a key enzyme in the promotion of uric acid. Febuxostat reduces blood uric acid level in gout patients with hyperuricemia , clinical studies show that the product is safe and effective, this product is metabolized by the liver, it does not depend on renal excretion, so for moderate - severe liver and kidney dysfunction patients it is not necessary to reduce the dose. Dose is once 1 day, 40 mg or 80 mg once ,it is not recommended for the treatment of gout patients without hyperuricemia.
4.Usage And Synthesis
Gout is a heterogeneous group of diseases, hereditary or acquired due to uric acid excretion decreasing and purine metabolism. Because the body produces too much uric acid and renal clearance capacity decreases, uric acid accumulates in the body, leading to urate crystals deposited in the joints and organs. Therefore, it means the treatment of gout usually taken to be: promote uric acid excretion, and suppression of uric acid, and adopt appropriate measures to improve related symptoms.
Uric acid formation is associated with purine metabolism, in the final step of purine metabolism, hypoxanthine becomes xanthine through the role of xanthine oxidoreductase (XOR) ,then further generate uric acid ,inhibiting activity of the enzyme can effectively reduce uric acid production. Febuxostat is currently the world's latest generation of non-purine selective inhibitor of xanthine oxidase, which acts highly selectively on the oxidase, then reduces uric acid synthesis, reduces uric acid levels, thus effectively treats ventilation diseases.
30 years, Allopurinol is the only clinically used drugs to inhibit production of uric acid and is used as gold drugs widely in clinical treatment of gout, and achieves good results in the anti-gout treatment. Compared with allopurinol, febuxostat has obvious advantages:
(1) allopurinol only inhibit reduced XOR while febuxostat shows a significant inhibitory effect on oxidized and reduced XOR , so its role of reducing the uric acid is more powerful, long-lasting;
(2) Because allopurinol is a purine analog,it is inevitable affecting other purine and pyridine metabolic activity . Therefore, allopurinol treatment should be repeated large doses of the drugs to maintain a high level. This also leads to serious or even fatal adverse reactions due to the accumulation of the drug-induced. However, Febuxostat as non-purine XOR inhibitors, has better security.
(2).Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
|State:||Liquid or Powder|
|Appearance:||White Crystalline Powder or Oil|
|Payment:||Western Union, Moneygram, T/T,Bitcion|
|Delivery:||We have stock, so we can delivery quickly at the very day when receive the payment. 100%Door to Door|
|Shipment:||Security Shipping:Shipping by express (FedEx,UPS,DHL,EMS), by air.The most professional forwarder would be recommanded for you.|
|Customs clearance||Don't have to worry about cystoms pass rate,our customs clearance is 100%|
|Product packing||The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also take into consideration .|
|After-sales service||Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.|
|Advantage of Our Company|
1,Professional medical products manufacture for more than 15 years
2,High quality with competitive price
3,Independent Design and Outstanding Sales Team
4,Large Supply Ability
5,Excellent after-sales service
1. Any Inquiries will be replied within 24 hours
2.Hight quality, fashion designs reasonable & competitive price. fast lead time.
3.Payment: You can pay for the order via: T/T, Western Union, MoneyGram
4. After Sale Service:
1).All products will have been strictly Quality Checked in house before packing.
2).All products will be well packed before shipping.
3)Parcel can be sent out in 24 hours after payment. Tracking number available
4)Secure and discreet shipment. Various transportation methods for your choice.
5)Customs pass rate ≥99%
6) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and
we have stock in there for transferring.
we have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air PostYou also can choose
your own shipping forwarder.
Sample Policy:You need pay for sample first if you want to check it and the money will be refunded when
mass order confirmed.
Payment Way: T/T,Western Union, Money Gram
Delivery Date: within 10 working days after deposit paid
Shipping Way: By Sea or By Air
After Service: When you receive the goods, please check the product and its quantity in time, Once
Problems arised , pls contact us and we will help you solve the problem.
1. How about the Delivery time?
We will arrange the delivery within 24 hours after receiving the payment,except for custom products.
2. What kind of payments does you support?
T/T, Western Union, PayPal & Cash are accepted.
3. What's the MOQ?
Generally speaking, the MOQ is 10 gram, but we also can provide you samples for quality inspection.
4. Do you charge for the samples?
According to our company policy, we just charge the samples based on EXW price. And we will return
the samples fee during the next order.
5. Can you packing according to customers' requirements ?
Sure,If you have a request for packing, please tell us,Any good ideas are welcomed.
6. Can you tell me your main customers?
That's our customer's privacy, we should protect their information.
At the same time, please rest assured that your information is also safe here.
We'll offer you the quotation as soon as possible once receive your inquiry, so don't hesitate to contact us.
|How to Proceed Your Orders?|
Please let me know the items you are favorable, quantities, and the destination country.
You confirm all details, and offer us purchasing order.
We send the detail price of our product and offer the suitable shipping method for reference.
You confirm the order and pay money 100% in advance and send us the detailed contacting information,
including contacting person/company, address, mobile number,ZIP code and your special requirements.
Parcel would be arranged within 12 hours upon receipt of your payment .
Photos would be offered to tell apart the products .
Tracking number :
Send by EMS, the tracking number is availabe within 12 hours . The info would be trackable that day or 1
If send by HKEMS or other express,the tracking number would be provided next day. And this does not
mean the info is trackable that day. It would be released on internet 2 or 3 days later . The reason why is
that parcel should be shipped to Hongkong from forwarder then wait for the flight .
You sign for the parcel , deliveried.
We offer after-sales service after you receive parcel.
|Any question, email me, I am sherry.|
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