Anti Estrogen Letro Zole Femara Steroid Powder for Women′s Health
|1 2 3 4 5+|
|FOB Unit Price:||US $30 US $25 US $20 US $15 US $10|
|Purchase Qty. (Bags)||FOB Unit Price|
|Production Capacity:||2000kgs Per Month|
|Payment Terms:||T/T, Western Union, Paypal, Money Gram, Bitcoin|
- Model NO.: Femara 5
- Customized: Non-Customized
- Suitable for: Elderly, Children, Adult
- Purity: >99%
- Minimum Order: Quantity:10g~1kg
- Delivery: Priority to The Use of DHL, TNT, FedEx, Hkems, UPS
- Lead Time: 4-6working Days
- Shelf Life: Two Years
- Contact: Alanyi
- Transport Package: as Customer Request
- Origin: Shanghai
- Powder: Yes
- Certification: GMP, ISO 9001, USP, BP
- State: Solid
- Delivery Time: Within 12hours After Payment
- Payment Terms: Western Union, Moneygram, T/T, Bitcoin
- Supply Ability: Adequate in Stock
- Storage: Ventilation Low Temperature Drying
- CAS: 00-00-0
- Trademark: ShuCan
- Specification: Pharmaceutical grade
- HS Code: 3301199000
GW 0742 www.shscsteroids.com
GW0742 is a high affinity PPAR agonist reduces lung inflammation induced by bleomycin instillation in mice.
A high throughput screening campaign was conducted to identify small molecules with the ability to inhibit
the interaction between the vitamin D receptor (VDR) and steroid receptor coactivator.
These inhibitors represent novel molecular probes to modulate gene regulation mediated by VDR. The peroxisome proliferator-activated receptor (PPAR) agonist GW0742 was among the identified VDR-coactivator inhibitors and has been characterized herein as a pan nuclear receptor antagonist at concentrations higher than 12.1 M.
The highest antagonist activity for GW0742 was found for VDR and the androgen receptor (AR). Surprisingly, GW0742 behaved as PPAR agonist/antagonist activating transcription at lower concentration and inhibiting this effect at higher concentrations. A unique spectroscopic property of GW0742 was identified as well. In the presence of rhodamine-derived molecules, GW0742+ increased fluorescence intensity and fluorescence polarization at an excitation wavelength of 595 nm and emission wavelength of 615 nm in a dose dependent manner.
The GW0742-inhibited NR-coactivator binding resulted in a reduced expression of five different NR target genes in LNCaP cells in the presence of agonist. Especially VDR target genes CYP24A1, IGFBP-3 and TRPV6 were negatively regulated by GW0742. GW0742 is the first VDR ligand inhibitor lacking the secosteroid structure of VDR ligand antagonists. Nevertheless, the VDR-meditated downstream process of cell differentiation was antagonized by GW0742 in HL-60 cells that were pretreated with the endogenous VDR agonist 1,25-dihydroxyvitamin D3.
ENDUROBOL is a selective agonist (activator ) of the PPAR receptor .It displays high affinity (Ki =1 nM ) and potency (EC50 =1 nM )for PPAR with >1000 fold selectivity over PPAR and PPAR.
It activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue ,and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome ,most likely by stimulating fatty acid oxidation .It has been proposed as a potential treatment for obesity and related conditions ,especially when used in conjunction with a synergistic compound AICAR ,as the combination has been shown to significantly increase exercise endurance in human .
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|No.||Steroid Raws||CAS No.||Concentration of cooking|
|2||10418-03-8||20mg/ml 100mg/ml 250 mg/ml|
|4||72-63-9||20 mg/ml 50mg/ml|
|5||Trenbolone acetate/ Finaject||10161-34-9||75mg/ml 100mg/ml 250mg/ml|
|6||Trenbolone enanthate||--||60mg/ml 100mg/ml 250mg/ml|
|7||Methenolone acetate/ Primobolan||434-05-9||20mg/ml 50 mg/ml|
|8||Metenolone enanthate/ Primobolan Depot||303-42-4||75mg/ml 100 mg/ml 200mg/ml|
|9||Drostanolone Propionate/ Masteron||521-12-0||75mg/ml100mg/ml 200mg/ml|
|10||Drostanolone enanthate/Masteron Enanthate||--||200mg/ml|
|11||--||100mg/ml 250mg/ml 400mg/ml|
|12||58-22-0||200mg/ml 250mg/ml 300mg/ml|
|13||Testosterone enanthate/ Delatestryl||315-37-7||100mg/ml 250mg/ml 500mg/ml|
|14||Testosterone acetate||1045-69-8||100mg/ml 200mg/ml 300mg/ml|
|15||Testosterone phenylpropionate/ TPP||1255-49-8||200mg/ml 250mg/ml 300mg/ml|
|16||Testosterone cypionate/ Depot Testosterone||58-20-8||150mg/ml 250mg/ml 300mg/ml|
|17||Testosterone propionate / Synovex||57-85-2||150mg/ml 250mg/ml 300mg/ml|
|18||Testosterone decanoate||5721-91-5||100mg/ml 200mg/ml 300mg/ml|
|19||Testosterone isocaproate||15262-86-9||100mg/ml 200mg/ml 300mg/ml|
|20||Testosterone undecanoate/ Nebido||5949-44-0||200mg/ml 250mg/ml 300mg/ml|
|22||Nandrolone Decanoate/ Deca Durabolin||360-70-3||50mg/ml 200 mg/ml 250 mg/ml|
|23||Nandrolone Phenypropionate/ Durabolin||62-90-8||150mg/ml 200mg/ml|
|24||Boldenone Cypionate||106505-90-2||25 mg/ml 100 mg/ml 200 mg/ml|
|25||Boldenone undecylenate(Equipoise)||13103-34-9||200mg/ml 300mg/ml 500mg/ml|
|26||Tamoxifen citrate||54965-24-1||20mg/ml 50mg/ml|
|27||Clomiphene citrate / Clomid||50-41-9||20mg/ml 50mg/ml|
|30||Femara 5||5 mg/ml|
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